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samtools-legacy.info | ||
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slack-desc |
SAM (Sequence Alignment/Map) format is a generic format for storing large nucleotide sequence alignments. SAM aims to be a format that: - Is flexible enough to store all the alignment information generated by various alignment programs - Is simple enough to be easily generated by alignment programs or converted from existing alignment formats - Is compact in file size - Allows most of operations on the alignment to work on a stream without loading the whole alignment into memory - Allows the file to be indexed by genomic position to efficiently retrieve all reads aligning to a locus. SAM Tools provide various utilities for manipulating alignments in the SAM format, including sorting, merging, indexing and generating alignments in a per-position format. NOTE! This is an older version of the program, kept here for compatibility with Ugene. You can safely install it along the new one. When you start Ugene, go to Settings > Preferences > External Tools and manually select the legacy binaries in /usr/bin/ Publication: Li H.*, Handsaker B.*, Wysoker A., Fennell T., Ruan J., Homer N., Marth G., Abecasis G., Durbin R. and 1000 Genome Project Data Processing Subgroup (2009) The Sequence alignment/map (SAM) format and SAMtools. Bioinformatics, 25, 2078-9. [PMID: 19505943]