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24 lines
1.2 KiB
Text
24 lines
1.2 KiB
Text
The cistrome refers to "the set of cis-acting targets of a trans-
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acting factor on a genome-wide scale, also known as the in vivo
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genome-wide location of transcription factor binding-sites or histone
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modifications". The term cistrome is a portmanteau of cistron + genome
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and was coined by investigators at the Dana-Farber Cancer Institute
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and Harvard Medical School.
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This is cistrome-conductGO (GO analysis): a galaxy tool to find the
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top-n highest expressed TFs. For a list of input genes, this tool uses
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R/BioC packages (GO, GOstats) to identify over represented GO terms.
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GO analysis depends on several R script tools (GOstats, GO.db,
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hgu133a.db, hgu133b.db, hgu133plus2.db, hgu95av2.db, mouse430a2.db,
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celegans.db, drosophila2.db, org.Hs.eg.db, org.Mm.eg.db, org.Ce.eg.db,
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org.Dm.eg.db). Visit https://bioconductor.org/ for details and see
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"biocondictor.txt" (also copied to the documentation folder of the
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created package) for batch installation of the required Bioconductor
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Packages.
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NOTE!
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This just repackages the script redistributed by the UniPro Ugene
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project, part of their External Tools package. This is the reason the
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homepage link points to Ugene. The source is hosted on Source Forge by
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the SlackBuild maintainer.
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