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12 lines
610 B
Text
12 lines
610 B
Text
Bowtie 2 is an ultrafast and memory-efficient tool for aligning
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sequencing reads to long reference sequences. It is particularly good
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at aligning reads of about 50 up to 100s or 1,000s of characters, and
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particularly good at aligning to relatively long (e.g. mammalian)
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genomes. Bowtie 2 indexes the genome with an FM Index to keep its
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memory footprint small: for the human genome, its memory footprint is
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typically around 3.2 GB. Bowtie 2 supports gapped, local, and paired-
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end alignment modes.
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Please cite:
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Langmead B, Salzberg S. Fast gapped-read alignment with Bowtie 2.
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Nature Methods. 2012, 9:357-359.
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