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32 lines
1.4 KiB
Text
32 lines
1.4 KiB
Text
GENECONV: Statistical Tests for Detecting Gene Conversion
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Gene conversion is any process that causes a segment of DNA to be
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copied onto another segment of DNA, or else appears to act in this
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way. The target segment can be on the same chromosome, on a different
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chromosome, or in a different organism. Short-segment gene conversion
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is an important force in evolution, and often takes place at a higher
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frequency than does point mutation.
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Given an alignment of DNA or protein sequences, GENECONV finds the
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most likely candidates for aligned gene conversion events between
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pairs of sequences in the alignment. The program can also look for
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gene conversion events from outside of the alignment. Candidate events
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are ranked by multiple-comparison corrected P-values and listed to a
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spreadsheet-like output file.
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IMPORTANT:
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You may get a "Segmentation fault" when running the program; the
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problem arises only when GENECONV writes to its log file (e.g.
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myfile.nex.sum), as opposed to its main output file myfile.nex.frags;
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the easiest workaround is to run GENECONV with the -nolog option:
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geneconv myfile.nex -nolog
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CITING:
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For references and citation information, check the documentation
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folder of the package.
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NOTE!
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The program GENECONV is free for academic use, but commercial rights are
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reserved. The program may be freely distributed for academic use, as
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long as it is not altered or renamed.
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