diff --git a/academic/biopython/biopython.SlackBuild b/academic/biopython/biopython.SlackBuild
index 458c4f38ff..d21249dac8 100644
--- a/academic/biopython/biopython.SlackBuild
+++ b/academic/biopython/biopython.SlackBuild
@@ -2,7 +2,7 @@
 
 # Slackware build script for biopython
 
-# Copyright 2019-2022 Petar Petrov slackalaxy@gmail.com
+# Copyright 2019-2023 Petar Petrov slackalaxy@gmail.com
 # All rights reserved.
 #
 # Redistribution and use of this script, with or without modification, is
@@ -25,7 +25,7 @@
 cd $(dirname $0) ; CWD=$(pwd)
 
 PRGNAM=biopython
-VERSION=${VERSION:-1.79}
+VERSION=${VERSION:-1.81}
 BUILD=${BUILD:-1}
 TAG=${TAG:-_SBo}
 PKGTYPE=${PKGTYPE:-tgz}
diff --git a/academic/biopython/biopython.info b/academic/biopython/biopython.info
index c47e4e9979..db278d6620 100644
--- a/academic/biopython/biopython.info
+++ b/academic/biopython/biopython.info
@@ -1,8 +1,8 @@
 PRGNAM="biopython"
-VERSION="1.79"
+VERSION="1.81"
 HOMEPAGE="https://biopython.org/"
-DOWNLOAD="http://biopython.org/DIST/biopython-1.79.tar.gz"
-MD5SUM="3c0e2dac4cf80f802c62effd788590f3"
+DOWNLOAD="http://biopython.org/DIST/biopython-1.81.tar.gz"
+MD5SUM="06cabd14f55d624db366ff75efb60ed2"
 DOWNLOAD_x86_64=""
 MD5SUM_x86_64=""
 REQUIRES="python2-numpy"