2013-01-13 10:29:11 +01:00
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Burrows-Wheeler Aligner (BWA) is an efficient program that aligns
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2016-11-26 22:19:25 +01:00
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relatively short nucleotide sequences against a long reference sequence
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such as the human genome. It implements two algorithms, bwa-short and
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BWA-SW. The former works for query sequences shorter than 200bp and the
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latter for longer sequences up to around 100kbp. Both algorithms do
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gapped alignment. They are usually more accurate and faster on queries
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with low error rates.
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A configuration file ("_aptx_configuration_file") will be used if it is
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in your $HOME. An example configuration file is available in
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/usr/share/archeopteryx.
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2013-01-13 10:29:11 +01:00
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If you use BWA-SW, please cite:
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Li H. and Durbin R. (2010) Fast and accurate long-read alignment with
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Burrows-Wheeler Transform. Bioinformatics, Epub.
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