mirror of
https://github.com/Ponce/slackbuilds
synced 2024-11-29 13:00:32 +01:00
18 lines
967 B
Text
18 lines
967 B
Text
|
Bowtie is an ultrafast, memory-efficient short read aligner geared
|
||
|
|
toward quickly aligning large sets of short DNA sequences (reads) to
|
||
|
|
large genomes. It aligns 35-base-pair reads to the human genome at a
|
||
|
|
rate of 25 million reads per hour on a typical workstation. Bowtie
|
||
|
|
indexes the genome with a Burrows-Wheeler index to keep its memory
|
||
|
|
footprint small: for the human genome, the index is typically about
|
||
|
|
2.2GB (for unpaired alignment) or 2.9GB (for paired-end or colorspace
|
||
|
|
alignment). Multiple processors can be used simultaneously to achieve
|
||
|
|
greater alignment speed. Bowtie can also output alignments in the
|
||
|
|
standard SAM format, allowing Bowtie to interoperate with other tools
|
||
|
|
supporting SAM, including the SAMtools consensus, SNP, and indel
|
||
|
|
callers.
|
||
|
|
|
||
|
|
If you use Bowtie for your published research, please cite:
|
||
|
|
Langmead B, Trapnell C, Pop M, Salzberg SL.
|
||
|
|
Ultrafast and memory-efficient alignment of short DNA sequences to
|
||
|
|
the human genome. Genome Biol 10:R25.
|